What’s The Difference Between The 2022 Nissan Murano vs. INFINITI QX50?

2022 Nissan Murano vs 2022 INFINITI QX50

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Built on a midsize platform, the 2022 Nissan Murano crossover SUV boasts premium amenities at reasonable prices. Designed for urban families, this two-row model wins the Top Safety Pick+ award by the IIHS. Made for the luxury segment, the 2022 INFINITI QX50 crossover SUV is much more expensive than the Nissan model.

2022 Nissan Murano

$32,910 – $46,160*

20/28 MPG

Miles per gallon (city/highway)**




Horsepower, 3.5-Liter V-6 Engine


$39,150 – $57,100

23/29 MPG

Miles per gallon (city/highway)




Horsepower, 2.0-Liter 4-Cylinder Engine

Technology Features

Technology Features

The 2022 Nissan Murano boasts the NissanConnect infotainment system, which has been revised and revamped for better connectivity. Featuring an 8.0-inch touch screen, the improved multimedia system offers full integration for iPhones through Siri Eyes Free and Apple CarPlay. If you own an Android device, you can activate Google applications through Android Auto. The Nissan Skill also provides easy interactions with Amazon Alexa. You’ll have plenty of remote features at your fingertips on the NissanConnect Services mobile application. The Nissan Door-to-Door Navigation and SiriusXM Traffic help you find the best routes for any travel or commute. Powered by INFINITI InTouch, the 2022 QX50’s infotainment center includes two independent displays with intuitive menus. However, you’ll have to dish out much more money on this high-end infotainment console, which is also compatible with the all-new IT Controller. Both crossover SUVs offer Wi-Fi connections and Bluetooth integration. Likewise, these premium family cars have USB ports in both rows. Designed by Bose, 11 speakers are optional on the 2022 Murano. Expect a much higher price label for the QX50’s Bose Performance Series audio system with 16 speakers.

Safety Features

Safety Features

Packing the next-generation Intelligent Shield 360 technologies, the 2022 Murano is one of the safest crossover SUVs ever launched by Nissan. You could buy this premium car with over ten accident-avoidance features, like the Intelligent Cruise Control and Intelligent Lane Intervention. Some warnings pop up on the 7-inch Advanced Drive-Assist Display, which has a custom menu. You can view 360-degree surroundings on the Intelligent Around View Monitor, which is directly linked to the NissanConnect infotainment monitor. Some other familiar crash-avoidance items on this acclaimed Nissan crossover SUV include the Rear Automatic Braking and Blind Spot Warning. Expect to pay more money for the comparable INFINITI Safety Shield. Even when loaded with such an expensive package, this luxury model still doesn’t qualify for the prestigious Top Safety Pick+ award from the IIHS.



The 2022 Nissan Murano boasts up to 67 cubic feet of cargo volume behind the first row. You can access the rear cargo area through the hands-free Motion Activated Liftgate. You’ll get just over 65 cubic feet of cargo space inside the 2022 QX50. However, this luxurious INFINITI model offers a three-zone climate control system. Having an effective range of 195 total feet, an electronic key manages the Nissan model’s Intelligent Climate Control. Besides having the unique Zero Gravity design, the 2022 Murano’s leather-appointed seats come with three modes for heating and ventilation. Likewise, the QX50’s leather-trimmed front seats include climate control.

Visit Our Dealership!

Let the experts at Kelly Nissan help you customize the 2022 Nissan Murano crossover SUV for a premium lifestyle. Visit our Nissan dealer in Oak Lawn, IL, to take a test drive!

*Price is Manufacturer’s Suggested Retail Price (MSRP). MSRP excludes tax, title, license, and documentary service fee. Dealer sets actual price.

**2022 EPA Fuel Economy Estimates. 20 City MPG / 28 Highway MPG / 23 Combined MPG for Murano®. Actual mileage may vary with driving conditions. Use for comparison only.